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1. Vitamin D deficiency is strongly linked to nonalcoholic fatty liver disease
2. Do you like Real Health Products?
3. Even Short Periods of Antibiotic Usage Affect Long-Term Gut Health
4. Florida Governor Bans Water Fluoridation Across the State
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Vitamin D deficiency is strongly linked to nonalcoholic fatty liver disease
Non-Alcoholic Fatty Liver Disease a growing metabolic disorder that often develops silently until serious damage occurs.
Research shows vitamin D controls liver function at the genetic level, activating fat-burning genes while suppressing fat storage, making it key for preventing and reversing liver damage.
Vitamin D supplementation in studies significantly decreased liver fat, reduced inflammation and restored proper mitochondrial structure and function, especially in older subjects.
Other essential nutrients for liver health include vitamins E, B12 and folic acid (B9), which work together to regulate fat metabolism, reduce inflammation and support detoxification
Practical solutions include eliminating vegetable oils, which are high in linoleic acid, strategic sun exposure, testing your vitamin D levels (aiming for 60 to 80 ng/mL) and combining vitamin D3 with magnesium and K2 when supplementing
One of the fastest-rising metabolic disorders today affects your liver, quietly and without warning. Nonalcoholic fatty liver disease, or NAFLD, is becoming alarmingly common worldwide, yet most people have no idea their liver is in trouble until serious damage sets in.
This isn't just a condition that strikes the unhealthy or overweight. A growing body of research is uncovering hidden drivers behind fatty liver, including something that rarely gets enough attention: nutrient depletion. And topping that list is vitamin D.
Vitamin D is often framed as a bone-health vitamin, but that's just a fraction of the story. Your liver relies on it to manage fat metabolism, regulate inflammation and maintain energy production inside your cells. As your vitamin D levels drop, which happens with age and indoor living, your liver's ability to function properly starts to break down.
The newest science reveals something even more urgent: vitamin D doesn't just support liver function; it controls it at the genetic level. This discovery has major implications for how to prevent, manage and even reverse liver disease tied to aging and metabolic stress.
Vitamin D Turns on a Key Switch That Stops Liver Fat in Its Tracks
A study published in Experimental & Molecular Medicine investigated how vitamin D3 supplementation affects age-related NAFLD.1 Researchers focused on the role of a mitochondrial protein that helps keep your liver cells' energy systems working. The goal was to understand how aging disrupts this process and how vitamin D restores it.
Older animals with low vitamin D had more fat in the liver — The study looked at 22-month-old mice, roughly the equivalent of humans in their 70s, compared with younger adult mice. Older mice with lower vitamin D levels had much higher fat accumulation in their livers, while those given high-dose vitamin D3 (20,000 IU/kg) saw marked improvement. Liver fat decreased, liver weight normalized and inflammation dropped significantly.
Fat-burning genes turned off with age but vitamin D turned them back on — In older animals, genes that break down fat were significantly suppressed. These are the genes your liver uses to burn fat for energy. Vitamin D supplementation switched them back on. It also lowered genes that drive fat storage. This dual action helps your liver shift away from fat storage and back into fat burning.
Fatty acid levels in the blood dropped with vitamin D — The aged mice supplemented with vitamin D had much lower circulating free fatty acids, which means the liver wasn't overwhelmed by incoming fat. It also indicated improved balance between fat uptake and fat breakdown, which is often lost in older adults with metabolic issues.
Vitamin D fixed mitochondrial structure — A mitochondrial protein that helps organize the mitochondria's inner structure was almost completely lost in the livers of older mice. Without it, mitochondria lose their ability to generate energy and burn fat. Vitamin D directly boosted levels, which helped mitochondria recover their normal structure and function. This was confirmed through imaging and molecular testing.
Aging cells hoard fat, but vitamin D turns that around — To test whether the specific mitochondrial protein loss alone caused aging, researchers gave healthy liver cells a dose of the drug doxorubicin to simulate aging. The mitochondrial protein tanked, and the cells quickly began storing fat and showing signs of cellular aging. Vitamin D helped undo the damage by clearing out fat and turning off the signs of cell aging.
Vitamins Regulate Liver Function at a Deep Molecular Level
In a related study published in Liver Research, scientists examined how key vitamins impact the progression of NAFLD.2 They explored how vitamin deficiencies, particularly in vitamins D, E, B9 and B12, play a role in disrupting liver metabolism. The study emphasized that without adequate levels of these nutrients, your liver's ability to manage fat breaks down, triggering a cascade of inflammation, insulin resistance and oxidative stress that accelerates disease progression.
Connections exist between vitamin levels and the severity of liver damage — The researchers found that people with lower levels of vitamins D and B12 had more advanced liver damage, and vitamin E deficiency was linked to a greater risk of inflammation and scarring in liver tissue.
Different vitamins impact your liver in very different ways — Vitamin E emerged as a powerful antioxidant, helping to cool down inflammation, stop fat buildup and even prevent cells from dying.
Meanwhile, vitamin D helped regulate immune responses and insulin sensitivity, while folate and B12 influenced methylation — a process that helps your liver detoxify and metabolize nutrients. Each of these vitamins played a distinct role in either worsening or improving NAFLD outcomes, depending on whether you were getting enough.
Vitamin D deficiency was strongly linked to insulin resistance and poor liver function — The researchers explained that vitamin D deficiency appears in 55% of people with NAFLD, and that low levels of this nutrient worsen insulin resistance, one of the main drivers behind fat buildup in your liver.
Vitamin D was found to improve how the pancreas secretes insulin and how cells throughout the body respond to it. Without enough vitamin D, your liver becomes more insulin-resistant, meaning it stores more fat instead of burning it.
Vitamin D also modulated the immune system's activity in the liver — Your liver is deeply involved in your immune function. The study showed that vitamin D helps regulate immune cells in the liver, especially through a family of receptors that are often activated by toxins and bacterial fragments in the blood. When these receptors are overstimulated, as they often are in vitamin D deficiency, they produce a flood of inflammatory molecules that damage liver cells.
Deficiencies in these vitamins disrupted liver repair and worsened metabolic damage — Without enough of these nutrients, your liver struggles to regenerate, detoxify and balance fat metabolism. These disruptions are compounded by modern diets and environmental stressors, making a healthy whole food diet and vitamin support helpful for those facing liver health issues.
We recommend PureLife Care+ but if you're not getting fast enough results, testing your Viramin D levels and improving it would help. Take a walk in the sun every day - even 20 minutes will make a real difference. (and more you can do ... read the link below.
Want to know more about a Fatty Liver and PureLife Care+ for Fatty Liver?
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When you refer friends and family who then purchase from RHP, you can receive a 10 percent discount on your next order of up to 6 bottles.
This discount is on top of any other discount you may already be getting, such as our Autoship or bulk ordering discount, which allows even our Autoship and bulk ordering customers an option to save even more!
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• If you have friends or family who might need one of our products, tell them about us!
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Even Short Periods of Antibiotic Usage Affect Long-Term Gut Health
Bacteria develop antibiotic resistance through multiple mechanisms with resistant strains persisting in the gut for approximately one year.
Even brief antibiotic use permanently alters gut microbiome diversity, with resistant bacteria multiplying and beneficial strains being eliminated, creating long-term gut problems.
A country's overall antibiotic consumption directly impacts an individual’s gut health. High antibiotic-use nations carry more antibiotic resistance genes even without taking antibiotics themselves.
Protecting gut health involves avoiding antibiotics, consuming probiotic-rich foods daily.
Antibiotic abuse is a pervasive public health concern around the world.
According to the U.S. Centers for Disease Control and Prevention (CDC), 2.8 million cases of antibiotic-resistant infections are diagnosed yearly, and 35,000 people die from it. But how do bacteria evade antibiotics, exactly? As it turns out, bacteria are hardy microorganisms that adapt to antibiotics in different ways: Read more www.mercola.com
Build a strong microbiome which creates better immunity and better health.
Read: Improving your Metabolism
Florida Governor Bans Water Fluoridation Across the State
Florida became the second U.S. state to ban water fluoridation after Governor DeSantis signed legislation calling it "forced medication" without informed consent; the ban takes legal effect July 1, 2025 — that’s when public water systems must stop adding fluoride and state regulators can begin enforcement.
A National Toxicology Program review of 72 studies found consistent evidence that fluoride exposure lowers children's IQ scores and impairs cognitive development.
Multiple states including Ohio and Texas are considering similar bans while federal agencies reevaluate fluoride recommendations under new leadership.
Research links fluoride to thyroid dysfunction and neurological harm, with doses as low as 2 to 5 milligrams daily affecting hormone regulation
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